Atypical Chronic Myeloid Leukemia
نویسندگان
چکیده
منابع مشابه
How I treat atypical chronic myeloid leukemia.
Atypical chronic myeloid leukemia, BCR-ABL1 negative (aCML) is a rare myelodysplastic syndrome (MDS)/myeloproliferative neoplasm (MPN) for which no current standard of care exists. The challenges of aCML relate to its heterogeneous clinical and genetic features, high rate of transformation to acute myeloid leukemia, and historically poor survival. Therefore, allogeneic hematopoietic stem cell t...
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According to the 2008 World Health Organization classification, chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia are rare diseases. The remarkable progress in our understanding of the molecular genetics of myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms has made it clear that there are some specific genetic abnorm...
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Chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) are rare entities grouped into the World Health Organisation (WHO) categories myeloproliferative and myelodysplastic/myeloproliferative neoplasms (MPN and MDS/MPN overlap), respectively. According to the WHO 2008 classification, both entities are characterized by leukocytosis and a hypercellular bone marrow, predom...
متن کاملIdentification of risk factors in atypical chronic myeloid leukemia.
In the WHO classification atypical chronic myeloid leukemia (CML) has been considered as a new distinct clinical entity included in the category of mixed myeloproliferative/myelodysplastic disorders. Little is known about this uncommon disease, whose incidence is about of one-two cases every 100 cases of Ph-positive CML. We analyzed our series of 55 patients diagnosed as having aCML, with the a...
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| 1634 | haematologica | 2009; 94(12) The World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues includes within myeloid neoplasms the category “Myelodysplastic/myeloproliferative neoplasms”. According to Vardiman et al., these are “clonal myeloid neoplasms that at the time of initial presentation have some clinical, laboratory or morphologic findings tha...
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ژورنال
عنوان ژورنال: Blood
سال: 2018
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2018-99-110189